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The effect of normalization methods on the identification of differentially expressed genes in microarray data (Computer/Bioinformatics Project)

In this study the effect of normalization methods on the identification of differentially expressed genes is investigated. A zebrafish microarray dataset called Swirl was used in this thesis work. First the Swirl dataset was extracted and visualized to view if the Continue reading

Semi-Automatic Translation of Medical Terms from English to Swedish: SNOMED CT in Translation (Computer/Biomedical Project)

The Swedish National Board of Health and Welfare has been overseeing translations of the international clinical terminology SNOMED CT from English to Swedish. This study was performed to find whether semi-automatic methods of translation could produce a satisfactory translation while requiring Continue reading

Development of Database Support for Production of Doubled Haploids (Computer/Biomedical Project)

In this project relational and Lotus Notes database technology are evaluated with regard to their suitability in providing computer-based support in plant breeding in general and specifically in the production of doubled haploids. The two developed databases are compared based on Continue reading

Modeling of the arterial system with an AVD implanted (Electrical/Biomedical Project)

The number of patients that are waiting for heart transplants far exceed the number of available donor hearts. Left Ventricular Assist Devices are mechanical alternatives that can help and are helping several patients. They work by taking blood from the left Continue reading

The Role of DAP-Kinase in Modulating Vascular Endothelial Cell Function Under Fluid Shear Stress (Biomedical Project)

Atherosclerosis preferentially develops in vascular regions of low or disturbed flow and high spatial gradients. Endothelial cells that line the vessel walls actively participate in translating mechanical stimuli, shear stress due to fluid flow, into intracellular signals to regulate cellular activities. Atherosclerosis is a chronic disease. During its development, Continue reading

Preparation and Evaluation of Antibacterial Dental Glass-ionomer Cements (Biomedical Project)

The functional quaternary ammonium salts (QAS) and their constructed polyQAS or PQAS were synthesized, characterized and formulated into a novel antibacterial glass-ionomer cement. Compressive strength (CS) and Streptococcus mutans (S. mutans) viability were used to evaluate the mechanical strength and antibacterial activity of the cements. Fuji II LC cement was used as control. The specimens were conditioned in Continue reading

Biomechanics of the Intervertebral Disc: The Effects of Load History on Mechanical Behavior (Mechanical Project)

Degenerative disc disease is associated with back pain, and can be a debilitating disorder. In addition to the biological contributions of genetics and aging, mechanical factors have been implicated in accelerating the progression of disc degeneration.

Two studies were performed in order to explore the effects of various loading conditions on disc biomechanics. The first study explores the effects of compressive historical loads and disc hydration on Continue reading

Ultrasound Imaging: Signal Acquisition – New Advanced Processing for Biomedical and Industrial Applications (ECE/Biomedical Project)

Use of ultrasound, namely in the biomedical diagnosis and industrial fields, pioneered in 1950s, is today particularly widespread. In the last decades, ultrasound imaging has benefited from advances in numerical technologies such as signal processing. On the other hand, the use of ultrasound imaging has increased the need for signal processing techniques.

This paper presents a review and the up-to-date developments in ultrasound imaging techniques, including Continue reading

Plaque Identification using Automated Image Enhancement

Image enhancement is a task of applying certain transformations to an original image for obtaining output image visually more pleasant, more detailed, or less noisy. The transformation usually requires interpretation and feedback from a human evaluator for the output result image. In this project we introduce automatic image enhancement techniques which are helpful in Continue reading